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Manufacturers supply cost-effective and customizable N-METHYLBARBITURIC ACID 2565-47-1
- Molecular Formula: C5H6N2O3
- Molecular Weight: 142.114
- Vapor Pressure: 0.000478mmHg at 25°C
- Melting Point: 132 °C
- Refractive Index: 1.503
- Boiling Point: 279.7°Cat760mmHg
- PKA: pK1:4.35(＋1) (25°C)
- Flash Point: 122.9°C
- PSA： 75.09000
- Density: 1.379g/cm3
- LogP: -1.22080
N-METHYLBARBITURIC ACID(Cas 2565-47-1) Usage
InChI:InChI=1/C5H6N2O3/c1-7-4(9)2-3(8)6-5(7)10/h2H2,1H3,(H,6,8,10)
2565-47-1 Relevant articles
Convenient synthesis of toxoflavin that targets β-catenin/TCF4 signaling activities
Mao, Yongjun,Tian, Wang,Huang, Ziwei,An, Jing
, p. 594 - 597 (2014)
A rapid and improved route for synthesis...
Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations
Zilly, Felipe E.,Taglieber, Andreas,Schulz, Frank,Hollmann, Frank,Reetz, Manfred T.
, p. 7152 - 7154 (2009)
A light-driven deazaflavin-dependent dir...
Robust Photocatalytic Method Using Ethylene-Bridged Flavinium Salts for the Aerobic Oxidation of Unactivated Benzylic Substrates
Pokluda, Adam,Anwar, Zubair,Boguschová, Veronika,Anusiewicz, Iwona,Skurski, Piotr,Sikorski, Marek,Cibulka, Radek
supporting information, p. 4371 - 4379 (2021/04/02)
7,8-Dimethoxy-3-methyl-1,10-ethyleneallo...
NOVEL CRYSTAL FORM OF PRODUCTION INTERMEDIATE OF ALOGLIPTIN BENZOATE
-
Paragraph 0035, (2020/05/02)
PROBLEM TO BE SOLVED: To provide a metho...
Synthesis method of 6-chloro-3-alkyl uracil
-
Paragraph 0030-0031; 0047-0048; 0050-0051, (2019/12/02)
The invention relates to a synthesis met...
A curved geleg sandbank preparation method
-
Paragraph 0050; 0052; 0053; 0066; 0068; 0069; 0082; 0084, (2019/04/04)
The invention claims a curved geleg sand...
2565-47-1 Process route
-
-
141-82-2
malonic acid
-
-
598-50-5
N-Methylurea
-
-
2565-47-1
1-methyl-2,4,6-pyrimidinetrione
| Conditions | Yield |
|---|---|
|
With
acetic anhydride;
at 70 ℃;
for 2h;
|
82%
|
|
With
acetic anhydride; acetic acid;
at 70 - 90 ℃;
for 3h;
Temperature;
|
78%
|
|
With
acetic anhydride;
In
acetic acid;
at 90 ℃;
for 16h;
|
76%
|
|
With
acetic anhydride; acetic acid;
a) 90 deg C, 6 h, b) overnight;
|
72%
|
|
With
acetic anhydride;
In
acetic acid;
at 90 ℃;
|
65.8%
|
|
With
acetic anhydride;
In
acetic acid;
at 70 - 90 ℃;
for 3h;
|
65.8%
|
|
With
acetic anhydride;
In
acetic acid;
at 70 - 90 ℃;
for 3h;
|
65.8%
|
|
With
acetic anhydride; acetic acid;
at 70 - 90 ℃;
for 3h;
|
64%
|
|
With
acetic anhydride; acetic acid;
at 60 - 90 ℃;
|
|
|
With
acetic anhydride; acetic acid;
|
|
|
With
acetic anhydride; acetic acid;
Reflux;
|
|
|
With
acetic anhydride;
Microwave irradiation;
|
-
-
105-53-3
diethyl malonate
-
-
598-50-5
N-Methylurea
-
-
2565-47-1
1-methyl-2,4,6-pyrimidinetrione
| Conditions | Yield |
|---|---|
|
N-Methylurea;
With
sodium;
In
ethanol;
for 1h;
diethyl malonate;
In
ethanol;
for 24h;
Reflux;
|
82%
|
|
With
sodium methylate;
In
methanol;
for 12h;
Reflux;
|
66%
|
|
With
sodium methylate;
In
methanol;
Yield given;
1.) 10 min, reflux, 2.) 6 h, 110 deg C;
|
|
|
|
|
|
With
sodium ethanolate;
In
ethanol;
Reflux;
|
|
|
With
sodium;
In
methanol;
for 18h;
Solvent;
Reflux;
|
2565-47-1 Upstream products
-
89284-14-0
5,5-dibromo-1-methyl-barbituric acid
-
141-82-2
malonic acid
-
108-24-7
acetic anhydride
-
598-50-5
N-Methylurea
2565-47-1 Downstream products
-
98655-72-2
1-methyl-5-(2-phenyl-chromen-4-ylidene)-pyrimidine-2,4,6-trione
-
27425-10-1
3-methyl-7-phenyl-1,5-dihydro-pyrano[2,3-d ]pyrimidine-2,4-dione
-
27425-23-6
6-bromo-3-methyl-7-phenyl-1,5-dihydro-pyrano[2,3-d ]pyrimidine-2,4-dione
-
52119-20-7
1-methyl-4,6-dimethoxy-2-oxo-1,2-dihydropyrimidine
