Factory supply 2-CHLORO-6-NITROPHENOL 603-86-1 with low price
- Molecular Formula: C6H4ClNO3
- Molecular Weight: 173.556
- Appearance/Colour: yellow crystalline powder
- Vapor Pressure: 0.0908mmHg at 25°C
- Melting Point: 67-71 °C
- Refractive Index: 1.5810 (estimate)
- Boiling Point: 217.3 °C at 760 mmHg
- PKA: 5.43±0.24(Predicted)
- Flash Point: 85.2 °C
- PSA： 66.05000
- Density: 1.554 g/cm3
- LogP: 2.47700
2-CHLORO-6-NITROPHENOL(Cas 603-86-1) Usage
InChI:InChI=1/C6H4ClNO3/c7-4-2-1-3-5(6(4)9)8(10)11/h1-3,9H/p-1
603-86-1 Relevant articles
Preparation method of Eltrombopag
-
Paragraph 0013; 0014, (2018/04/28)
The invention discloses a preparation me...
A ortho-nitro phenol and its derivative synthesis method (by machine translation)
-
, (2017/08/23)
The invention relates to a method for th...
Tertiary Butyl Nitrite Triggered Nitration of Phenols: Solvent- and Structure-Dependent Kinetic Study
Kumar, M. Satish,Rajanna,Venkateswarlu,Rao, K. Lakshman
supporting information, p. 171 - 196 (2016/04/09)
Nitration of phenols with tertiary butyl...
An ortho-nitro phenol synthetic method of compound
-
, (2016/10/10)
The invention relates to a synthesis met...
603-86-1 Process route
-
-
95-57-8
2-monochlorophenol
-
-
619-08-9
2-chloro-4-nitrophenol
-
-
603-86-1
2-chloro-6-nitrophenol
| Conditions | Yield |
|---|---|
|
With
silica supported Al(NO3)3*9H2O;
In
acetone;
at 20 ℃;
for 0.416667h;
regioselective reaction;
|
92%
4% |
|
With
sodium acetate; acetic acid; sodium nitrite;
In
water;
for 3h;
Ambient temperature;
|
7%
90% |
|
With
tert.-butylnitrite;
In
acetonitrile;
at 29.84 ℃;
Solvent;
Temperature;
Kinetics;
|
88%
|
|
With
ferric nitrate; 1,3-di-n-butyl-imidazolium tetrafluoroborate;
at 30 ℃;
for 1h;
|
78%
15% |
|
With
Montmorillonite KSF; nitric acid;
hafnium oxychloride;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
|
62%
35% |
|
With
ferric nitrate;
In
ethanol;
at 40 ℃;
for 2h;
|
35%
56% |
|
With
Yb-Mo-modified montmorillonite HKSF; nitric acid;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
|
54%
43% |
|
With
Eb-Mo-modified montmorillonite HKSF; nitric acid;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
|
48%
44% |
|
With
acetic acid; sodium nitrite;
In
cyclohexane; water;
for 3h;
Product distribution;
Ambient temperature;
variation of organic solvent or acetate buffer;
|
47%
43% |
|
With
acetic acid; sodium nitrite;
In
cyclohexane; water;
for 3h;
Ambient temperature;
|
47%
43% |
|
With
bismuth(III) nitrate;
at 20 ℃;
for 0.0833333h;
|
42%
35% |
|
With
nickel(II) nitrate hexahydrate;
In
tetrahydrofuran;
at 50 ℃;
for 4h;
Reagent/catalyst;
regioselective reaction;
|
36%
28% |
|
With
tetranitromethane;
In
cyclohexane;
at 20 ℃;
Product distribution;
Quantum yield;
Irradiation;
|
|
|
With
methanol; nitric acid;
|
|
|
With
nitric acid;
die beiden Isomeren werden durch die Barytsalze getrennt;
|
|
|
With
nitric acid;
In
acetic anhydride;
Title compound not separated from byproducts;
|
72 % Spectr.
28 % Spectr. |
|
With
nitric acid; acetic acid;
|
|
|
With
nitric acid; acetic acid;
|
|
|
With
nitric acid;
|
|
|
With
nitric acid;
In
acetic anhydride;
at -60 ℃;
for 0.25h;
Title compound not separated from byproducts;
|
28 % Spectr.
72 % Spectr. |
|
With
oxalic acid; silica gel; sodium nitrite;
In
dichloromethane;
at 20 ℃;
for 0.333333h;
Further Variations:;
Reagents;
Product distribution;
|
|
|
With
tert.-butylnitrite; silica gel;
In
acetonitrile;
at 100 ℃;
under 2250.23 Torr;
Time;
Temperature;
Pressure;
Overall yield = 98 %;
Microwave irradiation;
|
-
-
121-73-3
3-Nitrochlorobenzene
-
-
619-08-9
2-chloro-4-nitrophenol
-
-
89-64-5
p-chloro-o-nitrophenol
-
-
603-86-1
2-chloro-6-nitrophenol
| Conditions | Yield |
|---|---|
|
With
tert.-butylhydroperoxide; potassium tert-butylate; ammonia;
In
tetrahydrofuran;
for 0.25h;
|
3%
1% 79% |
|
With
potassium hydroxide; oxygen;
In
ammonia;
at -35 - -33 ℃;
for 5h;
Product distribution;
Mechanism;
|
.66 g
|
|
With
Cumene hydroperoxide; potassium tert-butylate;
In
ammonia;
at -33 ℃;
for 0.25h;
Yield given. Yields of byproduct given;
|
603-86-1 Upstream products
-
95-57-8
2-monochlorophenol
-
88-73-3
2-Chloronitrobenzene
-
88-75-5
2-hydroxynitrobenzene
-
121-73-3
3-Nitrochlorobenzene
603-86-1 Downstream products
-
946-31-6
2-chloro-4,6-dinitro-phenol
-
38191-33-2
2-amino-6-chlorophenol
-
80866-77-9
1-chloro-2-methoxy-3-nitro-benzene
-
59360-18-8
Benzyl-(2-chlor-6-nitrophenyl)-ether
