Quality Factory Sells Top Purity 99% 4,5-dihydro-6-methyl-2-phenylpyridazin-3(2H)-one 4578-58-9 with Safe Delivery
- Molecular Formula: C11H12N2O
- Molecular Weight: 188.229
- Vapor Pressure: 0.00103mmHg at 25°C
- Melting Point: 105-106 °C
- Boiling Point: 301.8°Cat760mmHg
- PKA: 1.90±0.20(Predicted)
- Flash Point: 136.3°C
- PSA： 32.67000
- Density: 1.14g/cm3
- LogP: 1.68990
4,5-dihydro-6-methyl-2-phenylpyridazin-3(2H)-one(Cas 4578-58-9) Usage
|
General Description |
4,5-dihydro-6-methyl-2-phenylpyridazin-3(2H)-one, also known as phenylpyridazinone, is a chemical compound with a molecular formula C12H12N2O. It is a heterocyclic organic compound with a pyridazin-3-one core structure. 4,5-dihydro-6-methyl-2-phenylpyridazin-3(2H)-one is commonly used in the field of medicinal chemistry and pharmaceutical research due to its potential as a bioactive agent. It has been studied for its potential anti-inflammatory, analgesic, and antioxidant properties. Additionally, it has been investigated for its potential use in the treatment of neurological disorders and as a building block for the synthesis of various pharmaceutical compounds. Its unique molecular structure and potential pharmacological properties make it an important target for further research and development in the field of drug discovery. |
InChI:InChI=1/C11H12N2O/c1-9-7-8-11(14)13(12-9)10-5-3-2-4-6-10/h2-6H,7-8H2,1H3
4578-58-9 Relevant articles
-
Lui,Warkentin
, p. 1767 (1972)
-
Synthesis and antiproliferative evaluation of spirothiadiazolopyridazine derivatives
Sekkak, Hanan,Mojahidi, Souad,Rakib, El Mostapha,Abouricha, Said,Kerbal, Abdelali,Aiello, Cinzia,Viale, Maurizio
, p. 743 - 746 (2013/01/09)
The 1,3-dipolar cycloaddition of N-aryl-...
An expeditious and environmentally benign methodology for the synthesis of substituted indoles from cyclic enol ethers and enol lactones
Singh, Pankajkumar R.,Surpur, Mandar P.,Patil, Sachin B.
, p. 3335 - 3340 (2008/09/21)
A simple and environmentally friendly me...
First synthesis of 4,5-dihydro-3(2H)-pyridazinones via Zn-mediated hydrohydrazination
Alex, Karolin,Tillack, Annegret,Schwarz, Nicolle,Beller, Matthias
, p. 4607 - 4609 (2008/09/21)
The hydrohydrazination of 4-pentynoic ac...
A General Synthesis of Substituted Indoles from Cyclic Enol Ethers and Enol Lactones
Campos, Kevin R.,Woo, Jacqueline C. S.,Lee, Sandra,Tillyer, Richard D.
, p. 79 - 82 (2007/10/03)
(Equation presented) A general method wa...
4578-58-9 Process route
-
-
591-12-8
5-methyl-2-furanone
-
-
59-88-1
phenylhydrazine hydrochloride
-
-
4578-58-9
4,5-dihydro-6-methyl-2-phenyl-3(2H)-pyridazinone
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
In
N,N-dimethyl acetamide;
at 100 ℃;
for 2h;
|
90%
|
|
With
montmorillonite K-10;
In
N,N-dimethyl acetamide; water;
at 80 ℃;
for 3h;
|
88%
|
-
-
123-76-2
levulinic acid
-
-
100-63-0
phenylhydrazine
-
-
4578-58-9
4,5-dihydro-6-methyl-2-phenyl-3(2H)-pyridazinone
| Conditions | Yield |
|---|---|
|
In
ethanol;
for 4h;
Reflux;
|
85%
|
4578-58-9 Upstream products
-
588-60-3
Levulinic acid phenylhydrazone
-
591-12-8
5-methyl-2-furanone
-
59-88-1
phenylhydrazine hydrochloride
-
123-76-2
levulinic acid
4578-58-9 Downstream products
-
38154-50-6
5-methyl-2-phenylpyridazin-3(2H)-one
-
5435-35-8
4-chloro-6-methyl-2-phenyl-2H -pyridazin-3-one
-
87780-11-8
phenyl-2 methyl-6 pyridazinethione-3
-
37986-38-2
2-(4-bromo-phenyl)-6-methyl-2H -pyridazin-3-one
