Factory supply good quality Z-ALA-GLY-OH 3235-17-4 with stock
- Molecular Formula: C13H16N2O5
- Molecular Weight: 280.28
- Vapor Pressure: 3.18E-14mmHg at 25°C
- Melting Point: 104 °C
- Refractive Index: 1.55
- Boiling Point: 578.5 °C at 760 mmHg
- PKA: 3.42±0.10(Predicted)
- Flash Point: 303.7 °C
- PSA： 104.73000
- Density: 1.285 g/cm3
- LogP: 1.28390
Z-ALA-GLY-OH(Cas 3235-17-4) Usage
|
Synthesis Reference(s) |
Tetrahedron Letters, 22, p. 1257, 1981 DOI: 10.1016/S0040-4039(01)90289-8 |
InChI:InChI=1/C13H16N2O5/c1-9(12(18)14-7-11(16)17)15-13(19)20-8-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,14,18)(H,15,19)(H,16,17)/t9-/m0/s1
3235-17-4 Relevant articles
Engineered Substrate for Cyclooxygenase-2: A Pentapeptide Isoconformational to Arachidonic Acid for Managing Inflammation
Kaur, Baljit,Kaur, Manpreet,Kaur, Navjot,Garg, Saweta,Bhatti, Rajbir,Singh, Palwinder
, p. 6363 - 6376 (2019/07/08)
Beyond the conventional mode of working ...
Synthesis of selenoxo peptides and oligoselenoxo peptides employing LiAlHSeH
Vishwanatha,Narendra,Chattopadhyay, Basab,Mukherjee, Monika,Sureshbabu, Vommina V.
experimental part, p. 2689 - 2702 (2012/06/01)
Synthesis of selenoxo peptides by the tr...
Chemical ligation of S-scylated cysteine peptides to form native peptides via 5-, 11-, and 14-membered cyclic transition states
Katritzky, Alan R.,Tala, Srinivasa R.,Abo-Dya, Nader E.,Ibrahim, Tarek S.,El-Feky, Said A.,Gyanda, Kapil,Pandya, Keyur M.
, p. 85 - 96 (2011/04/12)
Cysteine-containing dipeptides 3a-l, (3b...
Total Synthesis of Thymosin β4, 3. Conventional Synthesis of the Fragment of Thymosin β4
Link, Peter,Voelter, Wolfgang
, p. 1000 - 1008 (2007/10/02)
As part of our total synthesis of thymos...
3235-17-4 Process route
-
-
1142-20-7
N-Cbz-Ala
-
-
2503-31-3,3235-17-4,34286-66-3
N-benzyloxycarbonyl-L-alanylglycine
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
2: 47 percent / Et3
N / tetrahydrofuran; H2
O / 7 h / Ambient temperature
With
triethylamine;
In
tetrahydrofuran; water;
|
|
|
Multi-step reaction
with
2
steps
2: 63 percent / Et3
N / tetrahydrofuran; H2
O / 7 h / Ambient temperature
With
triethylamine;
In
tetrahydrofuran; water;
|
|
|
Multi-step reaction
with
2
steps
1: 87 percent / DCC / acetonitrile
2: 62 percent / Et3
N / H2
O / 12 h / Ambient temperature; pH=10.0
With
triethylamine; dicyclohexyl-carbodiimide;
In
water; acetonitrile;
|
|
|
Multi-step reaction
with
2
steps
1: DCC / ethyl acetate / 2.17 h / 0 °C
2: sodium hydrogen carbonate / H2
O; tetrahydrofuran / 0.08 h
With
sodium hydrogencarbonate; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; water; ethyl acetate;
|
|
|
Multi-step reaction
with
2
steps
1: 35 percent / DCC / CH2
Cl2
/ 10 h / Ambient temperature
2: Jones' reagent
With
jones' reagent; dicyclohexyl-carbodiimide;
In
dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: PCl3
2: dioxane; aqueous NaOH
With
1,4-dioxane; sodium hydroxide; phosphorus trichloride;
|
|
|
Multi-step reaction
with
2
steps
1: DCC, Et3
N / CHCl3
2: aq. NaOH / methanol
With
sodium hydroxide; triethylamine; dicyclohexyl-carbodiimide;
In
methanol; chloroform;
|
|
|
Multi-step reaction
with
2
steps
1.1: thionyl chloride / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: triethylamine / water; acetonitrile / Inert atmosphere
With
thionyl chloride; triethylamine;
In
tetrahydrofuran; water; acetonitrile;
|
|
|
Multi-step reaction
with
2
steps
1.1: chloroformic acid ethyl ester; triethylamine / tetrahydrofuran / 0.25 h / -10 °C
1.2: 13 h / -10 - 25 °C
2.1: sodium hydroxide / water; acetone / 0.75 h / 20 °C
With
chloroformic acid ethyl ester; triethylamine; sodium hydroxide;
In
tetrahydrofuran; water; acetone;
|
-
-
4840-29-3
Z-L-Ala-Gly-OMe
-
-
2503-31-3,3235-17-4,34286-66-3
N-benzyloxycarbonyl-L-alanylglycine
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
water; acetone;
at 20 ℃;
for 0.75h;
|
80%
|
|
With
sodium hydroxide;
In
methanol;
|
3235-17-4 Upstream products
-
2503-32-4
ethyl N-(benzyloxycarbonyl)-L-alanylglycinate
-
4840-29-3
Z-L-Ala-Gly-OMe
-
17126-93-1
Benzyloxycarbonyl-L-alaninphenylthiolester
-
56-40-6
glycine
3235-17-4 Downstream products
-
104173-18-4
N2 -(Benzyloxycarbonyl)-N1 -(methoxymethyl)-L-alaninamid
-
66962-63-8
C52 H64 N6 O15
-
112120-49-7
Z-(Ala-Gly)2-OMe
-
112120-50-0
Z-(Ala-Gly)3-OMe
