Factory Supply Industrial Grade (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetic acid 46989-59-7 with Best Price
- Molecular Formula: C14H17NO4
- Molecular Weight: 263.293
- Vapor Pressure: 3.9E-08mmHg at 25°C
- Boiling Point: 429.4°C at 760 mmHg
- Flash Point: 213.5°C
- PSA： 75.63000
- Density: 1.183g/cm3
- LogP: 2.25970
(R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetic acid(Cas 46989-59-7) Usage
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General Description |
The chemical (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetic acid, also known as etoricoxib, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Etoricoxib belongs to the class of selective COX-2 inhibitors, which are designed to specifically target the COX-2 enzyme responsible for inflammation, while avoiding the COX-1 enzyme that helps protect the stomach lining. This can help reduce the risk of gastrointestinal side effects commonly associated with traditional NSAIDs. Etoricoxib is available in various forms, including tablets, and should be used under the guidance of a healthcare professional. |
InChI:InChI=1/C14H17NO4/c1-3-19-12(16)9-10(2)15-13(14(17)18)11-7-5-4-6-8-11/h4-9,13,15H,3H2,1-2H3,(H,17,18)/b10-9-
46989-59-7 Relevant articles
Rectal absorption of lysozyme and heparin in rabbits in the presence of non-surfactant adjuvants
Miyake,Nishihata,Wada,Takeshima,Kamada
, p. 2020 - 2025 (2007/10/02)
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46989-59-7 Process route
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46989-59-7,91487-77-3,92246-50-9,114671-43-1
N- <1-methyl-2-ethoxycarbonyl-vinyl> -DL-α-amino-phenylessigsaeure
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DL-α-Amino-phenylessigsaeure, Acetessigester;
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141-97-9
ethyl acetoacetate
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56337-83-8
(R)-sodium 2-phenylglycinate
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46989-59-7
D-phenylglycine ethylacetoacetate enamine
| Conditions | Yield |
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In
ethanol;
Ambient temperature;
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46989-59-7 Upstream products
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141-97-9
ethyl acetoacetate
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56337-83-8
(R)-sodium 2-phenylglycinate
